Ten-month-old Lisa was last seen at her home in the 3600 block of North Lister Avenue in Kansas City, Missouri on October 3, 2011. Her mother, Deborah Bradley, put her to bed in her crib with her pacifier, blanket and some toys.
Deborah last saw Lisa at either 6:40 or 10:30 p.m. That evening, she was also caring for Lisa's two older half-brothers, who were asleep in another room. Deborah later admitted that she'd been drinking wine that night and had gotten drunk; she was also taking prescription medication for anxiety.
Lisa's father, Jeremy Irwin, an electrician, came home from work at approximately 4:00 a.m. the next morning and they discovered Lisa was gone. Several lights in the house were on, Lisa's bedroom window was open, the front door was unlocked and three cell phones were reportedly missing.
Lisa's parents called 911 to report her disappearance shortly at 4:00 a.m. and an extensive search of the immediate area turned up no sign of the baby.
Authorities stated Lisa's mother and father were less than cooperative with the investigation which is something Deborah and Jeremy denied. They were engaged to be married at the time of Lisa's disappearance, although Deborah was still legally married to another man, and had a six-year-old son by him.
By 2010, Deborah and her husband had been separated for about four years and he was serving in the Army. Her husband stated that he didn't believe Deborah would have harmed Lisa or been involved in her disappearance.
Three different witnesses saw a man walking down the road about three miles from Lisa's home at approximately 4:00 a.m. that night, carrying a baby dressed only in a diaper, but it's unclear whether the sightings are connected to Lisa's case.
Authorities haven't named any suspects in Lisa's disappearance. Her parents have stated they believe she was abducted from her home late on October 3rd or early on October 4th, possibly by a person who wanted to raise a baby.
As of 2018, Lisa's case remains unsolved.
Lisa is described as a Caucasian female with blonde hair, blue eyes, is 2'6 & 30 pounds. She has a birthmark on her right outer thigh, a small bug bite under her left ear and two of her bottom teeth had erupted by the time of her disappearance.
She was last seen wearing purple pants or shorts and a purple shirt with images of white kittens.